Sorafenib sensitizes (-)-gossypol-induced growth suppression in androgen ... - UroToday

Sorafenib sensitizes (-)-gossypol-induced growth suppression in androgen ... UroToday Here, we show for the first time, that treatment with (-)-gossypol and multikinase inhibitor sorafenib synergistically suppresses the growth of androgen-independent prostate cancer cells (AI-PC) in vitro and in vivo. Our data suggest that sorafenib ...

Study on the autophagy of prostate cancer PC-3 cells induced by oridonin ... - UroToday

Study on the autophagy of prostate cancer PC-3 cells induced by oridonin ... UroToday To investigate the mechanism of oridonin (ORI)-induced autophagy in prostate cancer PC-3 cells, PC-3 cells cultured in vitro were treated with ORI, and the inhibitory ratio of ORI on PC-3 cells was assayed by 3-4,5-dimethylthiazol-2-yl)-2,5-diphenyl ...